340B Management
340B Management products streamline the operational, financial, and compliance aspects of healthcare organizations’ 340B drug discount programs. These solutions automate eligibility verification, split billing, and contract pharmacy oversight, ensuring accurate discounts and audit readiness. By proactively identifying compliance risks and optimizing drug cost savings, these platforms reduce administrative burden and enhance pharmacy financial performance.These products typically differentiate through data integration capabilities: connecting seamlessly with EHRs, pharmacy information systems, wholesaler platforms, and external pharmacy networks. Advanced tools offer real-time analytics, customizable reporting, and proactive alerts, enabling teams to rapidly address discrepancies, maintain compliance, and optimize savings with minimal manual intervention.
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Alchemy
Alchemy
Company Info
Founded: 2023
Headcount: 11-50
Customers
Customers Served: Community Health Center, Government
Product Overview
Security and Compliance Certifications: HIPAA
Alchemy Health provides infrastructure for clinics to establish in-house pharmacies, focusing on 340B programs and public health entities like FQHCs, HIV clinics, and STD testing centers. They offer comprehensive support, including physical setup, staffing, and digital tools to manage operations, helping clinics maintain pharmacy ownership while outsourcing operations. Their platform also includes clinical programs to expand patient outreach, such as mobile testing services.
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Clearway Health
Clearway Health
Company Info
Founded: 2014
Headcount: 51-200
Customers
Verified Customers: 3
Customers Served: Hospital / Health System
Product Overview
Clearway Health provides specialty pharmacy services tailored to hospitals and health systems, focusing on program design, medication access, network expansion, and embedded clinical staff. Originating from Boston Medical Center Health System, the organization helps partners develop or enhance in-house specialty pharmacies, aiming to improve medication adherence, access for complex patients, and financial sustainability. Services include hands-on operational support, 340B program optimization, and integration with care teams to reduce barriers for vulnerable populations. It is used by health systems seeking to launch or strengthen specialty pharmacy programs with measurable clinical and financial outcomes.
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Kalderos
Kalderos
Company Info
Founded: 2016
Headcount: 51-200
Customers
Customers Served: Hospital / Health System
Product Overview
Security and Compliance Certifications: SOC 2 Type 2
Kalderos provides a drug discount management platform that helps stakeholders across the pharmaceutical ecosystem—such as manufacturers, covered entities, and state payers—monitor and resolve issues related to noncompliant drug discount claims. The platform uses AI and machine learning to analyze large volumes of claims data from Medicaid, commercial payers, and 340B programs to detect overlapping discounts and streamline compliance workflows. Kalderos supports direct communication between parties and offers tools like Truzo for organizing inquiries and strengthening audit processes. It is used by pharmaceutical companies and healthcare providers to reduce financial risk and maintain program integrity.
McKesson
Macro Helix
Company Info
Headcount: 10000+
Customers
Verified Customers: 5
Customers Served: Hospital / Health System
Product Overview
Macro Helix provides software and services for managing 340B drug pricing programs, with solutions designed for covered entities and contract pharmacies. Its core platform, 340B Architect, supports functions such as split billing, contract pharmacy administration, referral capture, audit preparation, and compliance monitoring. Additional tools include analytics for program performance, order optimization for central pharmacies, and management of manufacturer restrictions. Macro Helix is widely used by hospitals and health systems to maintain 340B compliance, improve operational efficiency, and support equitable access to medications.
Pillr Health
Pillr Health
Company Info
Founded: 2003
Headcount: 51-200
Customers
Customers Served: Hospital / Health System
Product Overview
Security and Compliance Certifications: SOC 2 Type 2
Pillr Health provides technology and services to optimize pharmacy operations, with a focus on supporting 340B programs for covered entities and pharmacies. Its platform includes solutions for split billing, contract and entity-owned pharmacy administration, audit support, compliance, and specialty pharmacy development. Additional offerings include analytics, program management, and consulting services to improve operational efficiency and regulatory adherence. Pillr is used by health systems, community health centers, and pharmacies to manage complex pharmacy workflows and ensure 340B program integrity.
Plenful
Plenful
Company Info
Founded: 2021
Headcount: 11-50
Customers
Verified Customers: 5
Customers Served: Pharmacies, Hospital / Health System
Product Overview
Security and Compliance Certifications: HIPAA
Plenful is an AI workflow automation platform designed for pharmacy and healthcare operations. It automates administrative tasks like 340B audits, documents processing for referrals, orders, and intake forms, contracted rates optimization & inventory planning, and pharmacy claims auditing. Plenful handles data formats including unstructured data as well as HL7v2, FHIR, REST APIs, and delimited text files.
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Proximity
Proximity
Company Info
Founded: 2023
Headcount: 1-10
Customers
Customers Served: Hospital / Health System, Ambulatory Practice
Product Overview
Proximity provides a digital platform that connects healthcare providers with nearby patients to improve appointment utilization and reduce no-shows. It identifies last-minute appointment openings and offers them to patients based on their location, preferences, and availability using automated outreach via text and mobile notifications. The platform integrates with scheduling systems and EHRs to update calendars in real time. Proximity is used by health systems, clinics, and urgent care centers to increase visit volume and improve access to care.
ProxsysRx
ProxsysRx
Company Info
Founded: 2013
Headcount: 51-200
Customers
Customers Served: Hospital / Health System
Product Overview
ProxsysRx provides pharmacy management and 340B optimization services for hospitals and health systems. Its offerings include retail pharmacy outsourcing, bedside prescription delivery, prescription payment assistance, and strategies to reduce readmission risk. The company also supports 340B ESP participation and employee health benefit alignment, often working under the hospital's brand with no upfront cost to the provider. ProxsysRx is used by health systems seeking to improve financial performance, expand pharmacy services, and enhance medication access for patients.
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SpendMend
SpendMend
Company Info
Founded: 1993
Headcount: 201-500
Customers
Verified Customers: 3
Customers Served: Hospital / Health System
Product Overview
SpendMend provides cost recovery and audit services for healthcare organizations, focusing on areas such as purchased services, pharmacy operations, and 340B program compliance. Their platform uses transaction-level analytics to identify overpayments, billing discrepancies, and missed contract terms, helping hospitals and health systems recover funds and reduce future leakage. They also offer support for 340B covered entities, including audit preparation and program optimization. SpendMend is used by healthcare finance teams to improve operational efficiency, increase visibility into spend, and drive sustained cost savings.
SunRx
SunRx
Company Info
Founded: 2006
Headcount: 51-200
Customers
Customers Served: Hospital / Health System
Product Overview
SUNRx provides a comprehensive suite of 340B program management services for hospitals, health centers, and pharmacies. Its platform includes tools for split billing, contract pharmacy management, compliance monitoring, audit support, and advanced claims capture, helping covered entities optimize savings while meeting federal requirements. SUNRx also offers specialty pharmacy support and technology solutions to streamline inventory and claims processing. It is primarily used by healthcare organizations seeking to improve medication access for underserved populations and ensure 340B program compliance.
Verity Solutions
Verity Solutions
Company Info
Founded: 2015
Headcount: 51-200
Customers
Customers Served: Hospital / Health System
Product Overview
Verity Solutions provides technology and administrative services to support 340B program compliance and pharmacy purchasing optimization for hospitals, health systems, community health centers, and contract pharmacies. Its platform offers features like inventory and split billing management, centralized oversight of third-party administrator (TPA) relationships, and data visibility across sites and pharmacy networks. Verity is used by healthcare organizations to manage 340B program requirements, reduce pharmacy costs, and ensure audit readiness. It also includes tools for tracking utilization, regulatory compliance, and cost savings.